I originally bought this for my dog with cancer and it helped him be less grumpy and he slept better. I think it made him eat more too. Now I'm using it for a dog with a lot of arthritis. She is perkier on it, but she is almost 15 and a half, so she sleeps pretty much all the time. Common drugs either do nothing (Carprofen) or make her act drunk and even more tired (gabapentin), so it's the best thing I can find. I'm back for a second bottle.